Rizal Irfandi, Muhammad Ilham, Erwing, Ruslang, Muhammad Arafah, Andi Badli Rompegading, Suriati Eka Putri, Suriana Dwi Sartika, Siti Fauziah, Ayu Safitri Agustina, Hairil Akbar, Ahmad Fudholi
Coronavirus Disease (COVID-19) is an infectious disease that has a high fatality rate and is spreading quickly throughout the world. The WHO claims that SARS-CoV-2, a brandnew coronavirus strain, is to blame for this outbreak (Severe Acute Respiratory Syndrome Corona Virus-2) and that COVID-19 must be treated with both conventional medical therapy and a combination of modern medicine. The technique of this study, a review of the literature, focused on numerous investigations looking at the potential of curcumin molecules from turmeric to cure the COVID-19 disease. Primary data for scientific papers is gathered from national and international journals through searches on electronic search engines like Google Scholar, Sciencedirect, or PubMed and selected publications are assessed, evaluated, and interpreted by authors. Turmeric contains substances that are immune system boosters, anti-inflammatory, antitumor, antiviral, and antioxidants. Curcumin may prevent a number of viral infections, according to evidence. In vitro testing has shown that the SARS-CoV virus is resistant to curcumin's antiviral properties. It's possible that curcumin can halt viral replication. Curcumin has the potential to treat COVID-19 effectively. Curcumin has antiviral activity that can fight the SARS-CoV-two virus. Treatment with curcumin can change the virus top protein structure, preventing the virus from entering the body and from budding. Future study on the use of curcumin as SARS-Cov-2 virus inhibitory agent is necessary in order to employ it as a novel and long-lasting therapy option for Covid-19 patients. © 2022 WITPress. All rights reserved.
Department of Biology Education, Faculty of Teacher Training and Education, Universitas Puangrimaggalatung, Sengkang, 90915, Indonesia; Department of Biology Education, Faculty of Teacher Training and Education, Universitas Muhammadiyah Bone, Bone, 92714, Indonesia; Department of Nursing, Faculty of Nursing and Midwifery, Universitas Puangrimaggalatung, Sengkang, 90915, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, Jalan Daeng Tata Raya Makassar, Makassar, 90244, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Bosowa, Makassar, 90244, Indonesia; Department of Industrial Engineering, Universitas Muhammadiyah Luwuk, Banggai, 94711, Indonesia; Department of Chemistry, Faculty of Science, Universitas Muhammadiyah Bulukumba, Jl. Ir. Soekarno No. 9, Ujung Bulu, Bulukumba, Sulawesi Selatan, 92513, Indonesia; Graha Medika Institute of Health and Technology, Kotamobagu, 9571, Indonesia; Solar Energy Research Institute, Universiti Kebangsaan Malaysia, Selangor, Bangi, 43600, Malaysia; Research Center for Energy Conversion and Conservation, National Research and Innovation Agency (BRIN), Serpong, 15314, Indonesia