Maming Maming, Fadliah Mubakira, Indah Raya, Bulkis Musa, Andi Muhammad Anshar, Erna Mayasari, Yusafir Hala, Syaharuddin Kasim, Ilham L. Andi, Gemini Alam, Andi Nilawati Usman, Hasmawati Hasmawati, Hasri Hasri, Andriani Usman, Rizal Irfandi
This study aims to know how to composite hydroxyapatite-collagen by freeze-drying method, and the characterization of hydroxyapatite-collagen composites using XRD, FTIR, and SEM. Hydroxyapatite nanocrystals are synthesized using the precipitation method by reacting CaO and (NH4)2HPO4 and the freeze-drying method in composite manufacturing by reacting hydroxyapatite nanocrystals with collagen. The results showed that hydroxyapatite nanocrystals can be composite with collagen using the freeze-drying method, and the results of characterization of XRD, FTIR, and SEM hydroxyapatite-collagen composites show the formation of chemical bonds between hydroxyapatite and collagen. The XRD spectrum of HAp-Collagen shows a peak at 2θ 10.45°, showing a physically formed composite. FTIR characterization shows the presence of absorption bands PO43- and OH- from HA, slight wavenumber shifts also occur in C-H, C-N, N-H, and C=O groups which are characteristic of collagen, this indicates that composites are formed physically. SEM characterization shows HAp is perfectly deposited into collagen molecules. © 2023 by SPC (Sami Publishing Company).
Department of Chemistry, Faculty of Mathematics and Natural Science, Hasanuddin University, Makassar, 90245, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Makassar, Makassar, 90245, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Makassar, 90245, Indonesia; Midwifery Study Program, Hasanuddin University, Makassar, 90245, Indonesia; Department of Matematics, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Makassar, 90245, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, Makassar, 90244, Indonesia; Department of Biology Education, Faculty of Teacher Training and Education, Universitas Puangrimaggalatung, Sengkang, 90915, Indonesia
