Iwan Dini, Nunuk Hariani Soekamto, Firdaus, Unang Supratman, Jalifah Latip
Alkaloid caulerpin (1), along with β-sitosterol (2), were isolated from the n-hexane extract of the macroalga Halimeda cylindracea Decaisne. The chemical structure was identified by a spectroscopic method including IR, MS, UV, NMR 1D, NMR 2D, and comparison with data of spectra previously reported. Compounds (1) and (2) were isolated for the first time from this macroalga. Compund (1) were evaluated for their cytotoxicity activity against NCL-H460 lung cancer cells in vitro and showed moderate activity with IC50 value of 20.05 µg/mL. © 2021 Penerbit Universiti Kebangsaan Malaysia. All rights reserved.
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Makassar, Makassar, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Hasanuddin, Makassar, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, Indonesia; Central Laboratory, Universitas Padjadjaran, Jatinangor, Indonesia; School of Chemical Science and Food Technology, Faculty of Science and Tecnology, Universiti Kebangsaan Malaysia, UKM, Selangor Darul Ehsan, Bangi, 43600, Malaysia
