New naphthoquinone derivatives from Fusarium napiforme of a mangrove plant

Closed

Unang Supratman, Nami Hirai, Shiho Sato, Keiko Watanabe, Abdul Malik, Suwardi Annas, Desi Harneti, Rani Maharani, Takuya Koseki, Yoshihito Shiono

2021 Natural Product Research Vol. 35 Issue 9 Article Cited by 33 Quartile

Abstract

Two new naphthoquinone derivatives, 6-hydroxy-astropaquinone B (1) and astropaquinone D (2) as well as the known compound 3-O-methyl-9-O-methylfusarubin (3) were isolated from Fusarium napiforme, an endophytic fungus isolated from the mangrove plant, Rhizophora mucronata. The structures of 1 and 2 were determined by 1D and 2D NMR spectroscopic analyses. Compounds 1, 2 and 3 exhibited moderate antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Furthermore, 1, 2 and 3 were phytotoxic action in lettuce seeding at a concentration of 30 μg · mL−1. © 2019 Informa UK Limited, trading as Taylor & Francis Group.

Affiliations

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang, Indonesia; Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, Japan; Department of Geography, Faculty of Mathematics and Natural Sciences, Universitas Negeri Makassar, Makassar, Indonesia; Department of Statistics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Makassar, Makassar, Indonesia