Cox Proportional Hazard Survival Analysis to Inpatient Breast Cancer Cases

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M. Nadjib Bustan, Arman, M.Kasim Aidid, Fatmah Afrianty Gobel, Syamsidar

2018 Journal of Physics: Conference Series Vol. 1028 Issue 1 Conference paper Cited by 7 Quartile

Abstract

Breast cancer problems are characterized by increased incidence and trends, including death. The prognosis of survival rate in 5 years in stadium I is 90%, stadium II 65%, stadium III 15-20%, and stadium IV is less than 5%. To determine survival rate and cause of death, survival analysis has been done to find the relationship between survival rate and clinical stages, tumor location, metastasis, age and co-morbidity. A retrospective cohort study of inpatient breast cancer cases in Ibnu Sina UMI Hospital, Makassar, Indonesia 2013-2016 was selected as 108 cases out of 436 all inpatient cases. The survival analysis was performed using Kaplan-Meier and Cox Proportional Hazard methods. The results showed that the survival probability was 0.029, and the median survival was 20 months at intervals from 0 to 46 months. Significant related factors with survival rete were metastasis and co-morbidity. The Hazard Ratio of cancer stadium II dan III was 2,061 and hazard ratio of cancer stadium IVwas 1.571. Moreover, Stadium III survival rate was 73.1%, and stadium IV / metastases decreased to 6.5%, but it was increased to 42.6% when treated. Suggestion of the need for early detection of breast cancer, so women should come early to visit health facilities. © Published under licence by IOP Publishing Ltd.

Affiliations

Department of Statistics, Makassar State University, Makassar, 90222, Indonesia; Post Graduate Program of Public Health, Universitas Muslim Indonesia, Makassar, 90232, Indonesia