Global stability of SIR and SEIR model for tuberculosis disease transmission with lyapunov function method

Open

Syafruddin Side, Wahidah Sanusi, Muhammad Kasim Aidid, Sahlan Sidjara

2016 Asian Journal of Applied Sciences Vol. 9 Issue 3 Article Cited by 35 SDG 3 Quartile

Abstract

Background and Objective: Tuberculosis (TB) is an infectious disease that poses a threat to the human population in the world. The aimed of study discussed are to build a model SIR and SEIR tuberculosis disease transmission and analysis for both models. Methodology: The SIR model is a system of ordinary differential equations four dimension and SEIR model is a system of ordinary differential equations five dimension. Both models are then analyzed by building a mathematical theorem, which guarantees the existence of a case of TB, the disease-free equilibrium phase and stage of disease endemic TB. Results: Three theorems proving using the Lyapunov function method. Basic reproduction number R0 also be obtained from the two models, namely, if R0>1 then obtained asymptotically stable equilibrium endemic globally and if the basic reproduction number R0≤1, acquired the disease-free equilibrium global asymptotically stable. Conclusion: The results of both models can be used to determine the status of TB disease in a region by conducting a simulation using data in the region. © 2016 Syafruddin Side et al.

Affiliations

Department of Mathematics, State University of Makassar, Indonesia; Department of Statistics, State University of Makassar, Indonesia

Research at a Glance

Premium content — register to unlock

Research at a Glance

Register to unlock

Topics & SDG Alignment

Premium content — register to unlock

Topics & SDG Alignment

Register to unlock

Collaboration

Premium content — register to unlock

Collaboration

Register to unlock

Author Profile (Selected)

Premium content — register to unlock

Author Profile (Selected)

Register to unlock

References Overview

Premium content — register to unlock

References Overview

Register to unlock

Journal & Source

Premium content — register to unlock

Journal & Source

Register to unlock

Metadata & Integrity

Premium content — register to unlock

Metadata & Integrity

Register to unlock