Fadliah Fadliah, Indah Raya, Ahyar Ahmad, Paulina Taba, Muhammad Burhannudinnur, Maming Gaffar, Tri Widayati Putri, Arfiani Nur, Andi Nur Fitriani Abubakar, Rachmin Munadi, Ahmad Fudhail Majid, Irham Pratama, M. Yasser, Sulistiani Jarre, Harningsih Karim
The potential uses of ecologically benign nickel nanoparticle manufacturing in various sectors, such as biomedicine, energy storage, and catalysis, have garnered much interest. This paper covers green approaches to nickel nanoparticle manufacturing, which integrate natural substances as stabilizing and reducing agents with eco-friendly processes. Phytochemicals derived from bacteria, microorganisms, and plant leaf extracts can convert nickel ions (Ni2+) into nickel nanoparticles. Room temperature is used for the synthesis procedure, and neither dangerous compounds nor unusual reaction conditions are used. Using a variety of analytical methods, the resultant nickel nanoparticles were characterized. We also investigate the possibility of using the generated nickel nanoparticles as a cytotoxic, photocatalytic, antioxidant, and antibacterial agents. The antimicrobial activity of nickel nanoparticles demonstrates their potent antibacterial properties, while their antioxidant activity demonstrates their capacity to combat free radicals effectively. Furthermore, nickel nanoparticles' cytotoxic activity demonstrates their capacity to kill cancer cells, and their photocatalytic activity demonstrates their efficiency in breaking down organic contaminants. This review highlights the value of ecologically benign synthetic methods and creates new avenues for developing nickel nanoparticle applications in health and the environment. © 2025, Gadjah Mada University. All rights reserved.
Doctoral Program, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10, Makassar, 90245, Indonesia; Department of Mining Engineering, Faculty of Earth and Energy Technology, Universitas Trisakti, Jl. Kyai Tapa No. 1, Jakarta, 11440, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10, Makassar, 90245, Indonesia; Department of Geological Engineering, Faculty of Earth and Energy Technology, Universitas Trisakti, Jl. Kyai Tapa No. 1, Jakarta, 11440, Indonesia; Department of Fishery Technology, Institute of Technology and Business Maritime Balik Diwa, Jl. Perintis Kemerdekaan VIII No. 8, Makassar, 90245, Indonesia; Department of Chemistry, Faculty of Science and Technology, Universitas Islam Negeri Alauddin Makassar, Jl. Sultan Alauddin No. 63, Makassar, 92113, Indonesia; Department of Chemistry, Faculty of Science, Universitas Muhammadiyah Bulukumba, Bulukumba, 92513, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Science, Makassar Islamic University, Jl. Perintis Kemerdekaan Km. 9, Makassar, 90245, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, Jl. Daeng Tata, Makassar, 90244, Indonesia; Department of Chemical Engineering, Universitas Fajar, Jl. Prof. Dr. H. Abdurrahman Basalamah No. 101, Makassar, 90231, Indonesia; Department of Chemical Engineering, Politeknik Negeri Ujung Pandang, Jl. Perintis Kemerdekaan Km. 10, Makassar, 90245, Indonesia; Department of Pharmacy, School of Pharmacy YAMASI, Jl. Mapala 2 Blok D5 No. 10, Makassar, 90222, Indonesia
