SURVIVAL ANALYSIS OF CORONARY HEART DISEASE PATIENTS: THE ROLE OF GENDER, HYPERTENSION, AND CLINICAL RISK FACTORS

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Bobby Poerwanto, Andi Ulfiana Fitri, Riska Yanu Fa’rifah, Rahmat Hidayat

2025 Communications in Mathematical Biology and Neuroscience Vol. 2025 Article Cited by 0 SDG 3SDG 17 Quartile

Abstract

Coronary heart disease (CHD) remains a leading cause of morbidity and mortality worldwide, with survival outcomes influenced by multiple demographic and clinical factors. This study aimed to identify prognostic determinants of recovery time among CHD patients using survival analysis. A retrospective dataset of 403 patients with con-firmed CHD was analyzed, excluding incomplete records. Patient characteristics were described, and the Cox proportional hazards model was applied to assess the effect of gender, age, hypertension, diabetes, and prior stroke on recovery time. The proportional hazards assumption was tested, and extended Cox models were considered where necessary. The results indicated that male gender and absence of hypertension were significant predictors of faster recovery, while age, diabetes, and history of stroke did not exhibit significant associations with recovery time. These findings are consistent with recent evidence that sex-related disparities and hypertension status play critical roles in shaping clinical outcomes in CHD patients. The study emphasizes the importance of incorporating these prognostic factors into treatment and rehabilitation planning to optimize patient management. Nevertheless, the conclusions are limited by the single-center design and modest sample size, and further multicenter research is recommended to confirm these findings and expand their generalizability. © 2025 the author(s).

Affiliations

Department of Statistics, Universitas Negeri Makassar, Makassar, 90222, Indonesia; Department of Information System, Telkom University, Bandung, 40257, Indonesia; Department of Health Administration, Universitas Negeri Makassar, Makassar, 90222, Indonesia

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